Résumé:
Ganglioneuroma is a benign tumor arising from the neural crest cells. This
tumor is rare compared to other benign neural tumors such as schwannoma
or neurofibroma. Most ganglioneuromas are diagnosed in young patients
and are most o en located in the posterior mediastinum followed by the
retroperitoneum.
Ganglioneuromas are benign tumors rarely di erentiate into malignant,
and di erentiation into malignant peripheral nerve sheath tumors (MPNST)
is extremely rare. To date, there are less than 20 reported cases of MPNST
arinsing from ganglioneuroma in the literature
We report a case of 24-year-old male with no history of childhood
neuroblastoma or a familial neurofibromatosis, who presented with an
adrenal gland mass discovered radiologically in the context of an exploration
of low back pain. Our finding demonstrated that, although rare, spontaneous malignant
transformation of ganglioneuroma into MPNST can occur.
